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External ID CCR6
Ensembl ID ENSG00000153467.4
Start 167445545
End 167461917
1 C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (LARC receptor) (GPR-CY4) (GPRCY4) (Chemokine receptor-like 3) (CKR-L3) (DRY6). [Source:SWISSPROT;Acc:P51684]
LocusLink Summary This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene
OMIM
601835
   
Genome View in Gbrowse CCR6
 
 
Gene with RefSeq(s) Refseq
Results
Antisense?
Locuslink (Gene) 1235

NM_031409
This variant (2) contains additional sequence within the 5' UTR, compared to transcript variant 1. Both variant 1 and 2 encode the same protein

No antisense detected
Locuslink (Gene) 1235

NM_004367
This variant (1) is the more frequent transcript. Both variant 1 and 2 encode the same protein

No antisense detected
Locuslink (Gene) 1235

NM_031409
This variant (2) contains additional sequence within the 5' UTR, compared to transcript variant 1. Both variant 1 and 2 encode the same protein

No antisense detected
Locuslink (Gene) 1235

NM_004367
This variant (1) is the more frequent transcript. Both variant 1 and 2 encode the same protein

No antisense detected
   
   
   
   
Other cDNA (No refseq) Emblid
  U45984
 
  Z79784
 
  U60000
 
  U68030
 
  U68032
 
  AY242126
 
  AL121935
 
  BC037960
 
  U45984
 
  Z79784
 
  U60000
 
  U68030
 
  U68032
 
  AY242126
 
  AL121935
 
  BC037960
 
  U45984
 
  Z79784
 
  U60000
 
  U68030
 
  U68032
 
  AY242126
 
  AL121935
 
  BC037960
 
  U45984
 
  Z79784
 
  U60000
 
  U68030
 
  U68032
 
  AY242126
 
  AL121935
 
  BC037960
 
  U45984
 
  Z79784
 
  U60000
 
  U68030
 
  U68032
 
  AY242126
 
  AL121935
 
  BC037960
 
  U45984
 
  Z79784
 
  U60000
 
  U68030
 
  U68032
 
  AY242126
 
  AL121935
 
  BC037960
 
           
           
 
Ensemble Mouse ID
External Mouse ID
Chromosome
% identity
Sequences
Results
Antisense?
ENSMUSG00000040899.1 Ccr6 17 74
Spidey
Antihunter
             
Cgap gene info 46468  
Top Ten All
Tissue Mormalized expr. Cluster clones : tissue clones
Bone_Marrow 54.31 1:29369
Lymph_Node 28.01 2:113869
mixed 10.15 2:314320
other 7.53 2:423795
Bone_Marrow 54.31 1:29369
Lymph_Node 28.01 2:113869
mixed 10.15 2:314320
other 7.53 2:423795
     
Tissue Development Stage Pathology
null null null
bone marrow 6 years myeloid
germinal center null normal
nasopharynx null normal
     
 
  Ontology Annotation Evidence Source
NM_004367 Molecular Function C-C chemokine receptor activity IEA GOA
NM_004367 Molecular Function Receptor activity TAS GOA
NM_004367 Molecular Function Rhodopsin-like receptor activity IEA GOA
NM_004367 Biological Process Antimicrobial humoral response (sensu Vertebrata) TAS GOA
NM_004367 Biological Process Cell motility TAS GOA
NM_004367 Biological Process Cellular defense response TAS GOA
NM_004367 Biological Process Chemotaxis TAS GOA
NM_004367 Biological Process Cytosolic calcium ion concentration elevation TAS GOA
NM_004367 Biological Process Humoral immune response TAS GOA
NM_004367 Biological Process G-protein coupled receptor protein signaling pathway IEA GOA
NM_004367 Biological Process Signal transduction TAS GOA
NM_004367 Cellular Component Integral to plasma membrane TAS GOA
NM_031409 Molecular Function C-C chemokine receptor activity IEA GOA
NM_031409 Molecular Function Receptor activity TAS GOA
NM_031409 Molecular Function Rhodopsin-like receptor activity IEA GOA
NM_031409 Biological Process Antimicrobial humoral response (sensu Vertebrata) TAS GOA
NM_031409 Biological Process Cell motility TAS GOA
NM_031409 Biological Process Cellular defense response TAS GOA
NM_031409 Biological Process Chemotaxis TAS GOA
NM_031409 Biological Process Cytosolic calcium ion concentration elevation TAS GOA
NM_031409 Biological Process Humoral immune response TAS GOA
NM_031409 Biological Process G-protein coupled receptor protein signaling pathway IEA GOA
NM_031409 Biological Process Signal transduction TAS GOA
NM_031409 Cellular Component Integral to plasma membrane TAS GOA
       
Antisense?
Mouse
antisense ?
Omim
Differential Expr.
EST contig

Osservations